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在扩展查建议期间,通过公共卫生监测报告的C型肝炎病毒检测,感染和病例,美国,2013-2021年

Kathleen N Ly¹, Justin K Niles², Ruth B Jiles¹

¹Division of Viral Hepatitis, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Public health reports (Washington, D.C. : 1974)

|February 12, 2024

概括

2013-2021年间,C型肝炎病毒 (HCV) 检测显著增加,这表明查工作有所改善. 尽管阳性率下降,但监测数据对于监测HCV消除进展至关重要.

科学领域:

肝病学和传染病的研究
公共卫生监督公共卫生监督
流行病学流行病学

背景情况:

型肝炎病毒 (HCV) 仍然是一个重要的公共卫生问题,是美国最常见的血液感染.
监测HCV检测,感染和病例报告的趋势对于评估消除目标的进展至关重要.

研究的目的:

评估2013年至2021年美国成年人中HCV检测,抗体和RNA阳性以及监视病例报告的趋势.
评估查策略的有效性,并确定HCV感染的人口变化.

主要方法:

使用的Quest诊断数据 (2013-2021) 针对HCV抗体和RNA测试趋势.
分析了型肝炎病例趋势的国家可通报疾病监测系统数据 (2013-2020年).
员工结合点回归分析测试和感染率的时间趋势.

主要成果:

每年HCV抗体测试从170万增加到480万;阳性率从5.5%下降到3.7%.
冠状病毒病毒RNA阳性从大约60% (2013-2015) 降至41.0% (2021),随着年龄人口结构的变化.
报告的型肝炎病例总体下降,但年轻成年人 (18-39岁) 中的比例增加.

结论:

增加HCV检测表明加强了普遍查协议.
多样化的数据来源对于全面监测HCV消除工作至关重要.
在HCV阳性方面,人口结构的变化凸显了针对性干预的必要性.

关键词:

在HCV病毒感染的过程中,型肝炎C型肝炎的发生实验室实验室实验室实验室实验室监控监督监督监督监督监督监督监督监督监督监督监督监督监督监督监督监督监督测试测试测试测试测试趋势趋势趋势

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