查克特神经关节病与下肢截肢后幻肢的更高率有关
Hannah H Nam1, Brandon J Martinazzi2, F Jeffrey Lorenz1
1Hershey, Pennsylvania, Penn State College of Medicine.
Foot & ankle specialist
|February 12, 2024
概括
切断截肢的Charcot神经关节病患者患有幻肢疼痛的风险更高. 这包括那些膝下截肢 (BKA) 和膝上截肢 (AKA) 的人.
科学领域:
- 医学研究 医学研究
- 临床结果 临床结果
- 糖尿病并发症 糖尿病并发症
背景情况:
- 幻肢疼痛发生率在接受重大截肢的Charcot神经关节病患者中不明.
- 查科神经关节病是糖尿病的严重并发症,影响脚和下肢.
研究的目的:
- 为了确定Charcot神经关节病是否会增加膝下截肢 (BKA) 或膝上截肢 (AKA) 后幻肢疼痛的风险.
- 为了比较糖尿病患者的幻肢疼痛率,有和没有切除后的Charcot神经关节病.
主要方法:
- 使用了TrinetX研究数据库 (2012-2022年) 与ICD和CPT代码.
- 确定了接受BKA的10,239名患者和接受AKA的6,122名患者.
- 在患有和没有Charcot神经关节病的糖尿病患者之间比较人口统计和幻肢疼痛风险.
主要成果:
- 在BKA后,Charcot神经关节病明显增加了幻肢疼痛的风险 (RR: 1.2,CI: 1.1-1.3).
- 查科特神经关节病也显著增加了AKA后幻肢疼痛的风险 (RR: 1.6,CI: 1.2-2.3).
- 两组之间没有发现显著的人口统计差异.
结论:
- 接受BKA或AKA治疗的Charcot神经关节病患者面临幻肢疼痛的风险增加.
- 这一发现强调了在截肢规划和疼痛管理中考虑Charcot神经关节病的重要性.
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