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直肠神经内分泌瘤的管理和监测:一个单中心的回顾性分析

Paige Barnard¹, Bree Stephensen¹, Georgia Taylor²

¹Department of Surgery and Critical Care, Sunshine Coast University Hospital, Sunshine Coast, Queensland, Australia.

ANZ journal of surgery

|February 12, 2024

概括

直肠神经内分泌瘤 (rNETs) 的发病率正在上升,但管理和监测缺乏一致的指导方针. 这项研究强调了需要改进内镜技术和对rNET进行标准化的跟进.

科学领域:

胃肠病学胃肠病学
在瘤学瘤学.
内镜检查是指内镜检查.

背景情况:

直肠神经内分泌瘤 (rNETs) 是罕见的,但发病率正在增加.
目前对rNET的管理和监督建议是基于有限的证据.
对rNET的后续做法往往是不一致和昂贵的.

研究的目的:

分析一个单一中心与rNETs的经验.
评估rNET发生率,管理实践,结果和遵守指南.
为了评估R1切除率和rNET患者的复发情况.

主要方法:

28个rNET案例的单一中心回顾性研究 (2012-2023年).
对发病率,管理,结果和遵守欧洲神经内分泌瘤学会 (ENETS) 指南的分析.
评估R1切除率,切除技术,病变识别和复发率.

主要成果:

观察到越来越多的rNETs发生率,与全球趋势保持一致.
在初始内镜中,R1切除率高 (75%),病变识别不佳和先进的内镜技术有限.
观察到不一致的后续实践和指导方针的遵守;33%的R1病例接受了监测,没有报告复发.

结论:

由于发病率不断上升,对rNET的标准化管理和监测至关重要.
需要加强在rNET识别和先进的内镜切除技术方面的培训.
需要进一步研究R1病例监测的长期结果和最佳内镜技术.

关键词:

R0 切除的切除方法在R1切除过程中.通过先进的内镜技术进行检查.直肠神经内分泌瘤是直肠的神经内分泌瘤.

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