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异常的压力通过WTAP/YTHDF2-依赖的TIMP3 m6A修饰促进椎间盘退化

Daokuan Gao1, Quanlai Zhao1, Chen Liu2

  • 1Department of Spine Surgery, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui, China.

Journal of cellular physiology
|February 12, 2024
PubMed
概括

异常的机械应力通过改变m6A修饰来加速椎间盘退化 (IDD). 这一过程通过减少TIMP3来降低核质矩阵,从而导致IDD的进展.

关键词:
细胞外矩阵是细胞外矩阵.椎间盘退化 椎间盘退化m6A甲基化 的情况.细胞核 细胞核 细胞核压力就是压力,压力就是压力.

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