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Updated: Jul 3, 2025

Imaging the Intracellular Trafficking of APP with Photoactivatable GFP
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识别有助于膜型5矩阵金属蛋白酶 (MT5-MMP) 处理粉样蛋白前体蛋白的结合伙伴

Hongjie Wang1, Madepalli K Lakshmana2, Gregg B Fields1

  • 1Department of Chemistry & Biochemistry, Institute for Human Health & Disease Intervention (I-HEALTH), Florida Atlantic University, Jupiter, Florida, USA.

Journal of cellular physiology
|February 12, 2024
PubMed
概括

阿尔茨海默病涉及粉样β斑.阿尔茨海默病涉及粉样β斑. 这项研究表明,膜型5矩阵金属蛋白酶 (MT5-MMP) 与粉样蛋白前体蛋白 (APP) 在各种细胞位置相互作用,增加粉样蛋白的产生. 特定的有约束力的合作伙伴增强了这种效果.

关键词:
阿尔茨海默病的疾病阿尔茨海默病的疾病.粉样蛋白前体蛋白质是粉样蛋白的前体.细胞内蛋白质溶解是细胞内的蛋白质溶解.膜类型的5矩阵金属蛋白酶.这是一个秘密,一个秘密,一个秘密.

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