Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Glial Cells01:04

Glial Cells

87.2K
Overview
87.2K
Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

1.3K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
1.3K
The Blood-brain Barrier00:49

The Blood-brain Barrier

47.4K
Overview
47.4K
Lysosomal Hydrolases01:22

Lysosomal Hydrolases

3.8K
Lysosomes are the site for the degradation of macromolecules and biological polymers released during membrane trafficking events such as secretory, endocytic, autophagic, and phagocytic pathways. The membrane-enclosed area of the lysosome, called the lumen, contains hydrolytic enzymes active in an acidic environment. These acid hydrolases are functional at a pH between 4.5 and 5 and are involved in cellular processes such as cell signaling, energy metabolism, restoration of the plasma membrane,...
3.8K
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

546
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
546
Neural Regulation01:37

Neural Regulation

39.4K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Efficient targeting of human glial progenitor cells in vivo with engineered AAV vectors and glymphatic delivery.

Nature biotechnology·2026
Same author

Noradrenergic infraslow rhythm during sleep is the critical link between heart-rate dynamics and memory consolidation.

bioRxiv : the preprint server for biology·2026
Same author

Enhanced glymphatic CSF tracer influx during α2-adrenergic agonist anesthesia is independent of tracer injection duration.

bioRxiv : the preprint server for biology·2026
Same author

Extending the glymphatic system beyond the brain: The Cochlear aqueduct as a neuroimmune gateway to the inner ear.

Neurobiology of disease·2026
Same author

Chronotherapy to reinforce circadian rhythms improves poststroke outcomes and glymphatic function in mice.

The Journal of clinical investigation·2026
Same author

Asymmetric Optic Disc Edema in Astronauts: A Narrative Review Proposing an Interplay Between Ocular Venous Congestion and Glymphatic Transport.

Life (Basel, Switzerland)·2026

相关实验视频

Updated: Jul 3, 2025

In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy
06:22

In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy

Published on: July 29, 2019

13.8K

神经退行性疾病中的淋巴系统功能障碍

Natalie Beschorner1, Maiken Nedergaard1,2

  • 1Center for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen N, Denmark.

Current opinion in neurology
|February 12, 2024
PubMed
概括

在像阿尔茨海默氏症这样的神经退行性疾病中,淋巴液运输被抑制. 未来的研究旨在了解淋巴细胞成像治疗的机制和诊断潜力.

科学领域:

  • 神经科学是一个神经科学.
  • 神经学 神经学
  • 生物医学工程 生物医学工程

背景情况:

  • 淋巴系统功能障碍越来越多地与神经退行性疾病有关.
  • 研究一致表明,与对照人群相比,阿尔茨海默病患者的脑液运输受损.

结论:

  • 淋巴系统损伤是神经退行性疾病的重要标志,特别是阿尔茨海默氏症.
  • 对淋巴抑制机制的进一步研究至关重要.
  • 淋巴成像对阿尔茨海默病的诊断和治疗策略具有前景.

更多相关视频

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
10:05

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy

Published on: May 22, 2020

10.2K
Cannula Implantation into the Cisterna Magna of Rodents
10:13

Cannula Implantation into the Cisterna Magna of Rodents

Published on: May 23, 2018

44.8K

相关实验视频

Last Updated: Jul 3, 2025

In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy
06:22

In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy

Published on: July 29, 2019

13.8K
Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
10:05

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy

Published on: May 22, 2020

10.2K
Cannula Implantation into the Cisterna Magna of Rodents
10:13

Cannula Implantation into the Cisterna Magna of Rodents

Published on: May 23, 2018

44.8K