GSK3α/β 抑制IFN-γ诱导的膜巨中的共刺激分子表达,限制CD4+ T细胞激活

Laurisa M Ankley1, Kayla N Conner1, Taryn E Vielma1

  • 1Department of Microbiology, Genetics, and Immunology, College of Osteopathic Medicine, Michigan State University, East Lansing, MI.

ImmunoHorizons
|February 12, 2024
PubMed
概括

肺部巨细胞,包括膜巨细胞 (AMs),对抗呼吸道病原体. 这项研究揭示了特定的激酶如何调节它们对干扰素- (IFN-γ) 的反应,影响炎症和T细胞激活.

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