与肥胖相关的高血压中心脏自主功能障碍的预测因素
Aqsa Mujaddadi1, Saima Zaki1, Majumi M Noohu1
1Centre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia (A Central University), New Delhi, 110025, India.
概括
与肥胖相关的高血压中的心脏自主功能障碍 (CAD) 是通过休息心率和身体脂肪百分比来预测的. 降低这些因素可能会降低受影响个体的心血管风险.
科学领域:
- 心脏病学 心脏病学
- 代谢健康 代谢健康
- 自主神经科学 自主神经科学
背景情况:
- 心脏自主功能障碍 (CAD) 是一个重要的,但经常被忽视的,与肥胖相关的高血压患者的心血管风险因素.
- 这种人群中CAD发病和进展的病理生理机制尚不清楚.
研究的目的:
- 确定心脏自主功能障碍 (CAD) 的潜在预测因子,特别是在与肥胖相关的高血压的背景下.
- 阐明生理标志物与CAD存在之间的关系.
主要方法:
- 72名患有肥胖相关高血压的参与者接受了全面评估,包括心脏自主功能测试,身体组成分析和生物化学评估.
- 参与者被分为CAD阳性或CAD阴性,使用Ewing的标准.
- 使用单变量和多变量逻辑回归分析来确定CAD的预测因素,并根据相关的共变量进行调整.
主要成果:
- 多变量分析确定了静止心率 (HRrest) 和人体脂肪百分比 (BF%) 作为CAD的显著独立预测因素.
- 确定了最佳截止值:HRrest> 74.1 bpm和BF%> 33.6%与增加的CAD风险有关.
- 差异通胀因子 (VIF) 低于3的值,表明没有显著的多对线性.
结论:
- 休息心率和身体脂肪百分比是肥胖相关高血压中心脏自主功能障碍的关键独立预测因素.
- 针对HRrest低于74.1bpm和BF%低于33.6%的治疗干预措施可能有助于减轻CAD风险.
- 需要进一步的研究来确定因果关系并探索额外的混变量.
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