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脂性核酸四酸盐化合物的抗病毒活性

Xiao Jia1, Dominique Schols2, Chris Meier1,3

  • 1Organic Chemistry, Department of Chemistry, Faculty of Mathematics, Informatics and Natural Sciences, Universität Hamburg, Martin-Luther-King-Platz 6, Hamburg D-20146, Germany.

Journal of medicinal chemistry
|February 12, 2024
PubMed
概括

研究人员开发了针对d4T核酸的新型核酸四酸原药. 这些前药物表现出有效释放活性代谢物和对艾滋病毒的显著抗病毒活性,证明了细胞膜通道的改善.

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