Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Autoregulation of Blood Flow01:17

Autoregulation of Blood Flow

2.3K
Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
2.3K
Neural Regulation of Blood Pressure01:18

Neural Regulation of Blood Pressure

2.8K
The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
2.8K
Arteries and Arterioles01:16

Arteries and Arterioles

3.7K
Arteries, the vasculature responsible for transporting blood from the heart, possess robust walls capable of enduring the elevated pressures exerted by the heartbeat. Arteries near the heart are especially thick-walled and enriched with elastic fibers across their three tunics, classifying them as elastic or conducting arteries. These arteries, usually with a diameter exceeding 10 mm, are characterized by their ability to dilate in response to the blood pumped from the heart's ventricles...
3.7K
Vascular Resistance01:20

Vascular Resistance

3.9K
Vascular resistance is a critical concept in understanding blood flow dynamics in the circulatory system. It refers to the resistance that blood encounters as it flows through the blood vessels. This resistance is a key factor in determining blood pressure and cardiac workload.
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
3.9K
Regulation of the Cardiovascular System01:27

Regulation of the Cardiovascular System

1.1K
The regulation of the cardiovascular system allows the body to adapt to various demands and maintain homeostasis.
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
1.1K
Arteries of the Lower Limbs01:24

Arteries of the Lower Limbs

190
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
190

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Novel Role of Von Willebrand Factor-αvβ3 Integrin in Human Pulmonary Artery Smooth Muscle Cell.

American journal of respiratory cell and molecular biology·2026
Same author

Resistance to age-related hypercoagulability: insights from the naked mole rat.

Research and practice in thrombosis and haemostasis·2026
Same author

Integrin α<sub>v</sub> contributes to the regulation of vascular smooth muscle cell stiffness.

Scientific reports·2026
Same author

A high level of sTREM-1 predicts occurrence of thrombosis, obstetrical event or death in a prospective cohort of patients with antiphospholipid antibodies and/or systemic lupus. Results of the APLART study.

Lupus·2025
Same author

Aging in the vascular system: lessons from mechanobiology, computational approaches, and oxidative stress.

Cardiovascular research·2025
Same author

Rethinking cardiovascular ageing.

Cardiovascular research·2025

相关实验视频

Updated: Jul 3, 2025

Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy
10:35

Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy

Published on: October 19, 2016

10.6K

动脉硬度:从基本的原始到整合性生理学

Véronique Regnault1, Patrick Lacolley1, Stéphane Laurent2

  • 1INSERM U1116, DCAC, Université de Lorraine, Nancy, France.

Annual review of physiology
|February 12, 2024
PubMed
概括

研究了动脉硬化,这是血管衰老和心血管疾病的关键因素. 本综述详细介绍了管理动脉硬性的生理机制和临床策略.

科学领域:

  • 整合生理学 整合生理学
  • 血管生物学 血管生物学
  • 心血管医学 心血管医学

背景情况:

  • 导电动脉的弹性性质是血液动力学的关键功能.
  • 动脉硬化与血管衰老和心血管疾病有关.
  • 了解这些属性的功能障碍对于临床结果至关重要.

研究的目的:

  • 提供对动脉硬化的整合生理学的新见解.
  • 审查动脉硬性的分子和途径决定因素.
  • 讨论临床进展和个性化治疗策略.

主要方法:

  • 基础科学和临床研究的综合文献综述.
  • 专注于机械传导,血管光滑肌细胞 (VSMC) 的可塑性和血管壁清除.
  • 检查免疫炎症和表观遗传机制.

主要成果:

  • 确定了动脉刚性的关键决定因素,包括VSMC收缩性和可塑性.
  • 突出了机械传导,血管壁清除和表型切换的作用.
  • 强调了对动脉硬性的免疫炎症和表观遗传影响.

结论:

关键词:
衰老的衰老 衰老的衰老表观遗传学是指表观遗传学.血液动力学 血液动力学免疫性炎症 免疫性炎症机械传导 机械传导血管光滑肌肉细胞的细胞.

更多相关视频

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound
10:08

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound

Published on: December 2, 2014

16.0K
Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
05:51

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

17.5K

相关实验视频

Last Updated: Jul 3, 2025

Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy
10:35

Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy

Published on: October 19, 2016

10.6K
Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound
10:08

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound

Published on: December 2, 2014

16.0K
Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
05:51

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

17.5K
  • 动脉硬化涉及复杂的生理和分子途径.
  • 在理解的进步导致修订治疗方法.
  • 基于风险的个性化策略正在出现,用于管理动脉硬.