低收入和中等收入国家对高脂血症药物的获取障碍
Chaoyang Li1, Garrison Spencer2, Muhammad Jami Husain1
1Division of Global Health Protection, Global Health Center, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
PLOS global public health
|February 12, 2024
概括
在低收入和中等收入国家,由于可用性较低和成本较高,对像他类药物这样的高脂血症药物的获取非常有限. 改善医疗保健系统和让私营部门参与,对于改善药物可访问性至关重要.
科学领域:
- 药物经济学 药物经济学
- 全球健康 全球健康
- 卫生系统研究 卫生系统研究
背景情况:
- 超脂血症对全球健康造成重大负担,但在低收入和中等收入国家 (LMICs) 中,有效的治疗方法面临着可访问性挑战.
- 了解超脂血症药物获取障碍对于改善资源有限的环境中的患者结果至关重要.
研究的目的:
- 识别和分析阻碍LMIC中高脂血症药物的可获得性的主要障碍.
- 评估在选择的LMICs的各种医疗保健机构中,对高脂血症的关键治疗方法他类药物的可用性和负担能力.
主要方法:
- 为了评估药物可访问性,采用了结合多个数据源的多方法分析.
- 数据收集包括评估公共和私人医疗保健设施中他类药物的可用性和成本.
- 进行了关键信息人采访,以收集对系统障碍的定性见解.
主要成果:
- 统计剂的可用性非常低,在公共设施中,原始药的中位数为0%,仿制药的中位数为5.4%,在私人设施中分别为13.3%和35.9%.
- 非洲和东南亚的可用性最差,私人设施的库存水平高于公共设施.
- 类药物是不可负担的,每月大约需要6天的工资,原始品牌比仿制药更昂贵.
结论:
- 跨多个卫生系统维度的重大障碍阻碍了LMICs中高脂血症药物的可访问性.
- 由于他类药物的可用性和负担能力较低,因此需要有针对性的干预措施.
- 建议包括加强卫生系统,让私营部门参与,教育医生,投资技术以改善医疗接入.
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