相关实验视频
Updated: Jul 3, 2025

08:03
In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
2.4K
神经外科手术后与伤口感染相关的风险和保护因素:元分析
Kang He1, Yan-Yang Li2, Hong-Lin Liu1
1Department of Neurosurgery, Huaihe Hospital of Henan University, Kaifeng, China.
International wound journal
|February 12, 2024
概括
潜在的疾病和紧急手术增加了骨切割后手术部位伤口感染的风险. 60岁以下的患者患上这些感染的风险较低.
科学领域:
- 神经外科 神经外科
- 传染病流行病学 传染病流行病学
- 医学统计 医学统计
背景情况:
- 神经外科切除术后的手术部位伤口感染 (SSWI) 对患者的康复构成重大风险.
- 识别和理解风险因素对于制定有效的预防策略至关重要.
研究的目的:
- 使用元分析系统地评估神经外科头骨切除术后SSI的风险因素.
- 提供基于证据的基础,用于预防骨切割患者的SSI.
主要方法:
- 在多个数据库 (PubMed,EMBASE,Cochrane Library,CNKI,Wanfang) 进行了全面的文献搜索,截至2023年11月.
- 数据提取和质量评估由两位研究人员独立进行.
- 用STATA 17.0软件对18项涉及17608名患者的研究数据进行了元分析.
主要成果:
- 分析包括18项研究,涉及17608名患者,其中905人患上SSI.
- 潜在疾病 (OR=2.50) 和紧急手术 (OR=2.47) 被确定为SSI的显著风险因素.
- 发现60岁以下的年龄 (OR=0.72) 是对SSI的保护因素. 性和抗微生物药物的使用与SSI风险没有显著关联.
结论:
- 潜在的健康状况和手术的紧迫性是切术后伤口感染风险的关键预测因素.
- 年龄<60岁与发生切后伤口感染的可能性降低有关.
- 这些证据支持针对性患者沟通和加强高风险个体的预防措施,以尽量减少SSWI的发生.
相关概念视频
Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
Healthcare Associated Infections II: Preventive Measures
2.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.6K
Infection
7.9K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.9K
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.2K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.2K
Local Anesthetics: Adverse Effects
414
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
414
Inflammatory Response II: Inflammatory Exudate and Tissue Repair
4.9K
The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
4.9K

