基斯托里普西:一种用超声波进行机械组织切除的方法
Zhen Xu1, Tatiana D Khokhlova2, Clifford S Cho3
1Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA;
Annual review of biomedical engineering
|February 12, 2024
概括
组织缩使用聚焦的超声波脉冲来液化组织,比热疗法更有优势. 这项创新技术正在用于各种医疗应用,包括癌症治疗.
科学领域:
- 医疗技术 医疗技术 医学技术
- 生物物理学的生物物理.
- 在瘤学瘤学.
背景情况:
- 基因组透是一种新的治疗超声波技术,它通过机械方式将组织分解成亚细胞碎片.
- 与传统的热疗法不同,基因组术提供精确的组织切除,并带来最小的附带损伤.
研究的目的:
- 为了审查的物理原理,参数,和硬件 histotripsy.
- 讨论生物效应和新兴的临床应用.
- 突出在各种医疗条件下组织缩的优势.
主要方法:
- 审查关于基因组的原则和应用的现有文献.
- 分析组织缩的物理机制,包括高振幅的聚焦超声脉冲.
- 检查成像方法,生物效应和硬件/软件参数.
主要成果:
- 基因组可以实现实时监测,清晰的损伤边缘和有效的组织去除.
- 该技术证明了组织选择性,保护关键结构并诱导免疫刺激.
- 临床前研究表明,在治疗癌症,血栓形成,血瘤和生物膜方面具有前景.
结论:
- 组织缩是一种有前途的非侵入性治疗选择,具有显著的临床优势.
- 美国食品和药物管理局对肝脏瘤的批准以及对其他疾病的正在进行的试验强调了其治疗潜力.
- 在瘤学和神经学中进一步研究基因组的应用是有必要的.
更多相关视频
07:38Real-time Monitoring of High Intensity Focused Ultrasound HIFU Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound HMIFU
Published on: November 3, 2015
10.0K
13:41Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
Published on: January 13, 2023
2.3K
相关概念视频
01:32Tissue Homogenization and Cell Lysis
7.5K
Tissue homogenization involves disintegrating tissue architecture and lysing cells, and is an early step in isolating and analyzing cellular components. The method used for homogenization depends on the sample type, the amount of sample available, the analyte to be obtained, and the sensitivity of the method. These methods are broadly classified as mechanical and non-mechanical methods.
Mechanical methods of tissue homogenization
These methods rely on applying external physical force to disrupt...
Mechanical methods of tissue homogenization
These methods rely on applying external physical force to disrupt...
7.5K
01:17Ultrasonography
4.5K
Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...
During an ultrasonography procedure, a handheld device called...
4.5K