THUBreast:一个开源的乳腺幻影生成软件,用于X射线成像和剂量测量
Jiahao Wang1,2, Yeqi Liu1,2, Ankang Hu1,2
1Department of Engineering Physics, Tsinghua University, Beijing 100084, People's Republic of China.
Physics in medicine and biology
|February 12, 2024
概括
新的乳房幻象准确地模拟了腺体分布,改善了乳房X射线成像和剂量测试中的虚拟临床试验的现实性. 与同质模型相比,这些幻影减少了辐射风险的高估.
科学领域:
- 医学成像物理 医学成像物理
- 计算解剖学的计算解剖学
- 放射性剂量测量 放射性剂量测量 放射性剂量测量
背景情况:
- 现实的乳房幻象对于乳房X射线成像中的虚拟临床试验至关重要.
- 现有的幻影往往缺乏精确的腺体分布,影响成像和剂量测量现实性.
- 这限制了虚拟试验在评估成像技术和辐射风险方面的可靠性.
研究的目的:
- 开发新的乳房幻象,结合现实的腺体分布.
- 创建一个开源软件工具 (THUBreast) 来生成这些先进的幽灵.
- 在成像纹理和辐射剂量测量方面验证THUBreast幻影的性能.
主要方法:
- 开发了THUBreast,这是一个开源软件,用于生成具有现实的结构纹理和腺体分布的乳房幻影.
- 创建了三个幻象组:THUBreast,基于患者的和同质的.
- 模拟的辐射和计算的功率定律指数 (β) 用于纹理现实性和平均腺体剂量 (Dg) 用于辐射风险使用MC-GPU.
主要成果:
- THUB乳房幻象显示了平均腺体剂量 (Dg) 值,与患者基幻象相比,平均偏差为4%.
- 与基于患者的幽灵相比,均质的幽灵高估了30%的平均Dg.
- THUBreast 幻影的平均功率法指数 (β) 为 2.92 ± 0.08,与之前的研究一致.
结论:
- THUBreast幻影在成像纹理现实性和辐射剂量测量方面表现良好.
- 这些幻影比同质模型更准确地代表了乳房解剖学.
- 在虚拟乳房X射线成像试验中,THUBreast提供了一种有价值的工具,用于提高图像质量和辐射风险的评估.
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