与日校相比,寄宿学校的青少年在自我报告的ART遵守率较低
Brenda Wandika1,2, Florence Nyapara1, Calvince Aballa1
1. Medical Research, Kenyatta National Hospital, Nairobi, Kenya.
Journal of acquired immune deficiency syndromes (1999)
|February 12, 2024
概括
寄宿学校的艾滋病毒感染者 (ALH) 青少年报告抗逆转录病毒疗法 (ART) 不遵守率较高. 学校的干预对于改善这种脆弱人群的治疗结果至关重要.
科学领域:
- 公共卫生 公共卫生
- 艾滋病毒/艾滋病研究研究
- 青少年医学 青少年医学
背景情况:
- 与成年人相比,艾滋病毒感染青少年 (ALH) 的抗逆转录病毒治疗 (ART) 坚持程度较低.
- 在撒哈拉以南非洲的寄宿学校环境中的耻辱可能会对ALH的ART坚持产生负面影响.
研究的目的:
- 为了比较肯尼亚的ALH白天学校与寄宿学校之间的ART坚持率.
- 为了确定与ART坚持相关的因素在上学ALH.
主要方法:
- 从肯尼亚的880名ALH (年龄14-19岁) 收集了社会人口统计数据,学校信息,病史和病毒载量数据.
- 用通用估计方程来比较日间和寄宿学校的学生之间的ART坚持.
- 与学校类型相关的自我报告的ART坚持和病毒载荷数据被分析.
主要成果:
- 在798名登记学校的ALH中,有189名 (24%) 进入寄宿学校.
- 与日间学校相比,寄宿学校的ALH更有可能自我报告缺失ART (aPR:1.47,p=0.001).
- 在寄宿学校 (51%) 与日间学校 (62%) 的ALH中,不可检测的病毒载量较低,尽管在统计学上不显著 (p=0.097).
结论:
- 在ALH中观察到高自我报告的ART不遵守,特别是那些在寄宿学校.
- 寄宿学校是一个关键的,但尚未充分利用的,为改善ALH的ART坚持和健康结果提供干预措施的环境.
- 需要有针对性的以学校为基础的计划来应对ALH面临的坚持挑战.
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