作为抗炎缓解治疗喘的抗炎缓解疗法,Budesonide/Formoterol或Budesonide/Albuterol可以使用
Brian Lipworth1, Chris RuiWen Kuo1, Kirsten Stewart1
1Scottish Centre for Respiratory Research, School of Medicine, University of Dundee, Ninewells Hospital, Dundee, United Kingdom.
The journal of allergy and clinical immunology. In practice
|February 12, 2024
概括
抗炎缓解剂 (AIR) 治疗将吸入性皮质类固醇 (ICS) 和缓解剂结合在一个吸入器中,改善了喘控制. 布德胺-甲醇 (BUD-FORM) 可以在喘严重程度上灵活使用,同时也建议使用布德胺-阿尔布醇 (BUD-ALB).
科学领域:
- 肺部病理学 肺部病理学
- 药理学 药理学是指药理学的学科.
- 喘管理 喘管理
背景情况:
- 低于最佳的喘控制与单独使用短效β-激动剂 (缓解剂) 和吸入性皮质类固醇 (ICS) (控制剂) 的吸入器有关.
- 将控制剂和缓解剂药物结合在单个吸入器中,称为抗炎缓解剂 (AIR) 疗法,可以改善喘结果.
研究的目的:
- 讨论抗炎缓解剂 (AIR) 治疗在喘管理中的作用.
- 在AIR治疗和维护方案中比较布德胺-阿尔布醇 (BUD-ALB) 和布德胺-形式醇 (BUD-FORM) 的治疗潜力.
主要方法:
- 审查当前的全球指导方针和AIR治疗的临床研究.
- 讨论布松胺 (BUD) 与阿尔布醇 (ALB) 或形式醇 (FORM) 结合使用,用于按需缓解症状和维持治疗.
主要成果:
- 全球指南支持BUD-ALB作为空气治疗来减少喘恶化.
- 单独使用的BUD-FORM允许在喘严重程度之间在AIR和维持和缓解疗法 (MART) 之间进行灵活的过渡.
结论:
- 需要进一步的对比研究来比较BUD-FORM与BUD-ALB作为轻度喘中的AIR治疗.
- 对于BUD-FORM在MART与BUD-ALB与维护ICS-LABA在中度至重度喘中进行的比较研究也表明了这一点.
- 与医疗保健专业人员一起以患者为中心的决策对于最佳的喘控制和遵守至关重要.
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