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Updated: Jul 3, 2025

Protein Purification-free Method of Binding Affinity Determination by Microscale Thermophoresis
10:22

Protein Purification-free Method of Binding Affinity Determination by Microscale Thermophoresis

Published on: August 15, 2013

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在没有化学分析的情况下测量热力学可溶性

Emma Hokkala1, Clare J Strachan1, Mikael Agopov2

  • 1Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Viikinkaari 5 E 00790, Helsinki, Finland.

International journal of pharmaceutics
|February 12, 2024
PubMed
概括

与传统的摇瓶 (SF) 方法相比,单颗粒分析 (SPA) 提供了一种更快,更有效的方法来确定药物化合物的可溶性. 通过SPA,实验时间从几天大幅缩短到几个小时,对各种化学分析的资源减少.

关键词:
解散 解散 解散 是一个过程.在HPLC中使用HPLC.质谱测量质量谱测量光学成像技术的使用.折射测量法 折射测量法 折射测量法单个粒子分析可溶性 溶解度 溶解度 溶解度

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