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Updated: Jul 3, 2025

Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel
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Published on: September 8, 2017

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利用表观遗传点来克服前列腺癌中对标素的抗性

Buse Cevatemre1, Ipek Bulut2, Beyza Dedeoglu3

  • 1Koc University Research Center for Translational Medicine, Istanbul, Turkey.

Cell death & disease
|February 12, 2024
PubMed
概括

基因和RING指域含有蛋白质 (BRPF) 的抑制通过向ABCB1流动,使得割抵抗性前列腺癌 (CR-PCa) 对分类基因重新敏感. 这种表观遗传策略恢复了药物易感性,并为抗性前列腺癌提供了新的治疗途径.

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