在调整年龄12个月以下的早产婴儿中检查功能性胃肠道疾病:前性队列研究
Yusuf Aydemir1, Ozge Aydemir2, Meltem Dinleyici3
1Faculty of Medicine Department of Pediatrics, Division of Gastroenterology and Hepatology, Eskisehir Osmangazi University, Meselik, 26040, Eskisehir, Turkey. dryusufaydemir@yahoo.com.
European journal of pediatrics
|February 12, 2024
概括
与满期婴儿相比,早产婴儿的功能性胃肠道疾病 (FGIDs) 比率更高,如结肠和便秘. 在前六个月的纯母乳养可以减少早产婴儿的发生率.
科学领域:
- 儿科 儿科 儿科
- 胃肠病学 胃肠病学
- 新生儿科学 新生儿科学
背景情况:
- 功能性胃肠道疾病 (FGIDs) 在婴儿期很常见,但对早产婴儿的数据有限.
- 患有慢性或复发性症状的FGID是由结构或生化异常无法解释的,并且可能与年龄有关.
研究的目的:
- 为了比较早产婴儿和早产婴儿之间的FGID频率.
- 调查新生儿特征与早产婴儿FGID发育之间的关联.
主要方法:
- 一项多中心前性队列研究,涉及134名早产婴儿和104名晚产婴儿.
- 婴儿在多个时间点使用罗马四号标准对FGIDs进行了评估,年龄修正至12个月.
- 过早出生的婴儿在12个月后接受了额外的随访,年龄修正.
主要成果:
- 过早出生的婴儿表现出更高的婴儿结肠,反综合征,功能性便秘和婴儿的发病率.
- 在前六个月的独家母乳养与早产婴儿的发病率较低 (18.8%与52.1%相比).
- 在早产婴儿中,FGID症状,特别是婴儿结肠和吐,在早产婴儿 (中位数为2个月) 中出现的时间较晚,而不是早产婴儿 (中位数为1个月).
结论:
- 早产婴儿患FGID的患病率明显高于满期婴儿.
- 对于早产婴儿,特别是那些有胃肠道疾病的婴儿,建议对FGID进行查.
- 成熟的差异可能会影响早产婴儿的FGID发病时间,纯母乳养可以预防婴儿.
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