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在患有病的儿童和年轻成年人中,向公平的移植取得了进展

Mercedes Harford¹, Marciana Laster²

¹Division of Nephrology, Department of Pediatrics, School of Medicine, Indiana University, 699 Riley Hospital Drive, Rm 230, Indianapolis, IN, 46202, USA.

Pediatric nephrology (Berlin, Germany)

|February 12, 2024

概括

尽管系统发生了变化,儿童移植中种族差异仍然存在. 需要进一步的研究,以解决少数民族儿童在获取和移植生存方面的剩余不平等问题.

科学领域:

儿科脏病学儿科脏病学
移植手术移植手术
健康公平卫生公平

背景情况:

儿科移植中的种族差异已经得到了充分的证据.
这些差异影响了预防性移植,候选名单,移植时间,活体捐赠和移植结果.
以前的器官分配系统变化 (Share 35,KAS) 部分解决了这些不平等问题,但没有完全解决.

研究的目的:

分析器官分配系统变化对儿科脏移植中种族种族差异的影响.
确定在移植获取和移植存活方面的持续差异.
探索健康的社会决定因素在调解这些差异中的作用.

主要方法:

20多年来对儿科移植数据的分析.
评估器官分配系统的变化,包括35份和分配系统 (KAS).
评估预防性移植,等待名单,移植时间,活体捐献和移植结果的差异.

主要成果:

器官分配系统的变化解决了一些,但并非全部的种族种族差异.
在预防性移植,等待列表的时间和活体供体移植方面仍然存在差异.
尽管在KAS下有所改善,但移植存活率的种族差异仍然存在.

结论:

儿童移植和移植存活率的种族差异是一个国际问题.
健康的社会决定因素 (金融准入,语言障碍,活体供体可用性) 显著调解了这些差异.
进一步调查可修改的社会,生物和文化因素对于消除移植结果差异至关重要.

关键词:

孩子孩子孩子孩子不平等的差异在脏 - 脏 - 脏种族种族种族种族社会决定因素社会决定因素移植移植移植移植

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