李斯特菌单细胞原生脑呈现出类似中风的症状:一个病例报告
Roxana M Dragomir1, Olivia Mattner1, Veronica Hagan2
1Neurology, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.
Cureus
|February 13, 2024
概括
本案例研究详细介绍了Listeria monocytogenes在免疫受损患者的脑. 及时诊断和用安培素和三甲胺硫治疗导致显著的恢复.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 大脑是罕见的,特别是那些由Listeria monocytogenes引起的.
- 免疫受损的个体有更高的机会性感染的风险,如李斯特菌病.
- 类似中风的症状可以掩盖脑的出现.
研究的目的:
- 报告一个Listeria monocytogenes脑的病例.
- 突出诊断挑战和治疗结果.
- 审查关于Listeria monocytogenes的有限文献.
主要方法:
- 一个免疫功能低下的患者的病例介绍,患有类似中风的症状.
- 诊断成像包括CT和MRI扫描.
- 血液培养和大脑活检用于病原体鉴定 (通过MALDI-TOF MS通过Listeria monocytogenes).
- 用安皮西林和三甲胺硫治疗.
主要成果:
- 在血液培养物中确定了Listeria monocytogenes,并通过脑活检确认.
- 患者出现了头痛和失言症,最初模仿中风.
- 图像检查显示左额叶病变与相一致.
- 治疗导致明显的症状改善和有利的临床过程.
结论:
- Listeria monocytogenes脑是一种罕见但可治疗的疾病.
- 早期诊断和适当的抗生素治疗对于有利的结果至关重要.
- 该患者符合Listeria monocytogenes的五项诊断标准中的三项.
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