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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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在测试免疫检查点抑制剂的随机临床试验中,整体生存的替代终点:系统性审查和元分析

Isabella Sala1,2, Eleonora Pagan1, Laura Pala3

  • 1Department of Statistics and Quantitative Methods, University of Milan-Bicocca, Milan, Italy.

Frontiers in immunology
|February 13, 2024
PubMed
概括

在免疫检查点抑制剂试验中,总生存的最佳代用终点是无进展生存 (PFS). 改性PFS (mPFS) 和受限平均存活时间 (RMST) 不是这些癌症治疗的可靠替代品.

关键词:
免疫检查抑制剂 (ICI) 免疫检查抑制剂免疫疗法 免疫疗法方法论 方法论 方法论随机的临床试验随机的临床试验代孕母亲是什么意思

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