在腹手术后与持续阻塞性睡眠呼吸暂停相关的因素:叙述性审查
Nathalie Demaeyer1, Marie Bruyneel1,2
1Department of Pneumology, CHU Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
Nature and science of sleep
|February 13, 2024
概括
阻塞性睡眠呼吸暂停 (OSA) 经常在减肥手术后持续存在,缓解率差异很大. 诸如年龄,手术前OSA严重程度和2型糖尿病等因素可能会影响OSA在手术后的持续性.
科学领域:
- 腹部外科和睡眠医学
- 阻塞性睡眠呼吸暂停 (OSA) 研究研究
- 肥胖和代谢健康 肥胖和代谢健康
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 影响了45-70%的减肥手术候选人.
- 减肥术后的减肥并不能保证OSA的缓解,这表明其他因素也有所贡献.
- 了解持续性OSA的预测因素对于管理肥胖患者至关重要.
研究的目的:
- 审查当前关于预测阻塞性睡眠呼吸暂停 (OSA) 在减肥手术后持续性的因素的文献.
- 综合评估腹部患者手术前和手术后OSA的研究结果.
主要方法:
- 对6项追溯和前性研究的系统综述,涉及1302名患有OSA的空腹患者.
- 纳入标准:>50名患者,手术前和手术后通过多重睡眠图 (PG/PSG) 进行OSA评估.
- 分析患者的人口统计 (BMI,年龄,性别) 和手术/诊断参数.
主要成果:
- 在手术后11-12个月,OSA缓解率差异很大 (26-76%).
- 潜在的OSA持续性预测因素包括年龄,手术前OSA严重程度,体重减轻比例和2型糖尿病 (T2D),尽管研究结果不一致.
- 对随访的高损失可能低估了真正的OSA缓解率.
结论:
- 减肥手术提供了可变的OSA缓解;除了体重减轻之外的几个因素影响了持续性.
- 年龄,最初的OSA严重程度,T2D和体重减轻幅度都与此有关,但需要进一步研究以确保一致性.
- 脂肪分布,种族和睡眠位置等其他因素在未来的多中心研究中需要进行调查.
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