自主功能障碍和运动不耐受性在COVID-19后 - 一个尚未被低估的器官系统?
F Schwendinger1, V N Looser2, M Gerber2
1Division of Sports and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Grosse Allee 6, 4052 Basel, Switzerland.
后COVID-19患者往往由于影响心脏,肺部和肌肉的因素而经历运动不耐受. 这项研究探讨了自主神经系统是如何导致这些持续症状的.
科学领域:
- 心血管呼吸系统生理学
- 自主神经系统功能自主神经系统功能
- 后COVID-19的后续影响
背景情况:
- 持续的症状,如运动不耐受和低心肺呼吸能力在COVID-19恢复过程中很常见.
- 瓦塞曼轮系统强调了心脏,肺部和肌肉的相互作用,以确定健康状况.
- 周围,心血管和肺部扩散限制是已知的COVID-19后运动不耐受性的贡献者.
研究的目的:
- 研究自主神经系统 (ANS) 在COVID-19后运动不耐受症中的作用.
- 为ANS参与运动不耐受性提出一种精神病理生理模型.
- 鼓励对导致COVID-19后症状的生理系统进行更广泛的检查.
主要方法:
- 审查和讨论关于ANS和运动生理学的现有文献.
- 确定四种潜在的途径,通过这些途径,ANS可能会导致运动不耐受.
- 将这些路径合成一个概念性精神病理生理模型.
主要成果:
- 在COVID-19后的运动不耐受性背景下,自主神经系统得到了有限的关注.
- 提出了四种关键途径:大脑血液动力学变化,异常的 afferent/efferent信号传递,中心过敏,以及身体活动评估/参与的变化.
- 这些途径为了解ANS对持续症状的贡献提供了一个框架.
结论:
- 自主神经系统是COVID-19后运动不耐受的一个关键因素,但尚未得到充分研究.
- 为了全面理解,需要考虑肺,心血管和外围因素的同时考虑ANS.
- 对ANS进行进一步的研究是有必要的,以开发针对COVID-19后运动不耐受症的有效干预措施.
更多相关视频
04:20Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
Published on: October 1, 2019
07:26Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
相关概念视频
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's...
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
