消极生活事件与青少年皮层结构连接之间的关系
Francesca Sibilia1, Coline Jost-Mousseau1,2, Tobias Banaschewski3
1Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.
青少年的负面生活事件并没有在全球范围内改变大脑结构. 然而,高压力与涉及情绪和注意力的特定大脑网络的变化有关,影响局部连接.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 脑部成像 脑部成像
背景情况:
- 青春期是一个关键的发育阶段.
- 负面的生活事件是神经精神疾病的危险因素.
- 了解压力对青少年大脑发育的影响至关重要.
研究的目的:
- 调查消极生活事件与青少年结构性大脑连接之间的关系.
- 为了检查图形理论网络措施和连接强度.
- 区分全球和地方网络层面的影响.
主要方法:
- 利用了来自IMAGEN联盟的结构性大脑网络 (n=487,扩展到n=976).
- 根据生活中发生的负面事件将参与者分为低压和高压分组.
- 采用图形理论分析,基于网络的统计数据和兴趣区域 (ROI) 方法.
主要成果:
- 没有观察到负面生活事件对全球网络措施的重大影响.
- 局部网络分析显示,体运动,视觉和背部注意力网络的中心性发生了变化.
- 在注意力,边缘和突出网络中,在高压力组中发现了连接强度的增加.
结论:
- 仅仅是负面的生活事件并不能在全球范围内改变青少年的结构性大脑连接.
- 压力与情绪和注意力相关的大脑区域内的局部连接的特定变化有关.
- 研究结果强调了压力对青少年大脑结构组织的微妙影响.
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