芬兰1987-2010年关突症的流行:基于人口的研究
Pia Vuola1, Niklas Pakkasjärvi2, Annukka Ritvanen3
1The Cleft and Craniofacial Center, Department of Plastic Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Birth defects research
|February 13, 2024
概括
1987-2010年间,芬兰鼻病的发病率有所增加,主要是由于综合征病例的增加. 与其他地区不同,芬兰没有看到metopiccraniosynostosis的显著增加.
科学领域:
- 儿科 儿科 儿科
- 遗传学 是一个遗传学.
- 公共卫生 公共卫生
背景情况:
- 头骨突发症是一种常见的头骨面部形.
- 对于芬兰,基于人口的流行病学数据有限.
- 本研究通过分析流行率和趋势来解决这一差距.
研究的目的:
- 估计芬兰骨突症的总和出生患病率.
- 检查1987年至2010年骨突症的时间趋势.
- 识别特定类型及其流行率.
主要方法:
- 利用了芬兰卫生和统计当局的全国性注册.
- 包括活产,死产和胎儿异常终止的数据.
- 医疗记录被专家审查以确认诊断.
主要成果:
- 确定了877例骨突症;83%是单突症.
- 活产儿患病率为6.0/10,000,从5.0增加到7.5/10,000 (1987-2010年). 在美国,活产儿患病率是6.0/10,000,从5.0增加到7.5/10,000.
- 总患病率从5.0上升到8.0/10,000;最常见的是斜突.
结论:
- 总的来说,部突症的患病率显著增加,主要是由于综合征病例.
- 穆恩克综合征有助于该综合征亚组内活产患病率的上升.
- 与全球其他地区不同的是,芬兰没有显著增加metopic craniosynostosis.
相关概念视频
01:22Sutures of the Skull
6.7K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
6.7K
01:14Cranial Bones: Superior and Posterior View
2.2K
The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
2.2K