对于治疗子宫内膜癌和复发期间的支持社会干预的研究协议 (SISTER研究):一个社区参与的国家随机试验
Ann Oluloro1, Bryan Comstock2, Sarah E Monsell2
1Department of Obstetrics & Gynecology, Fred Hutchinson Cancer Center, University of Washington, Seattle, WA 98195, USA.
Journal of comparative effectiveness research
|February 13, 2024
概括
在SISTER研究中,研究了高风险子宫内膜癌 (EC) 的黑人妇女的虚拟支持干预措施. 结果将显示这些干预措施是否改善治疗完成率并减少社会隔离,解决EC结果中的种族差异.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 健康差异 在健康上的差异
背景情况:
- 社会隔离对癌症患者的预后和治疗坚持有负面影响.
- 与白人患者相比,患有子宫内膜癌 (EC) 的黑人女性的社会隔离率更高.
- 解决社会隔离对于改善高风险EC患者的治疗结果至关重要.
研究的目的:
- 评估虚拟支持干预措施在改善高风险EC的黑人妇女治疗完成的有效性.
- 将虚拟支持干预与增强常规护理和促进支持小组进行比较.
- 确定在这个人群中提供社会支持干预措施的障碍和促进者.
主要方法:
- 一个多站点,前性,开放标签,社区参与的随机对照试验 (SISTER研究).
- 三个支部:增强的常规护理,便利的支持小组和一对一的同行支持.
- 主要结局:相对剂量;次要结局:社会隔离得分,定性访谈.
主要成果:
- 主要分析使用治疗意图和多变量模型.
- 将使用归纳和演内容分析分析定性数据.
- 这项研究旨在确定社会支持干预措施对治疗完成和社会隔离的影响.
结论:
- 子宫内膜癌死亡率不成比例地影响黑人女性,社会隔离导致这种差异.
- 该SISTER研究将提供对高风险EC黑人妇女有效社会支持策略的见解.
- 研究结果旨在通过有针对性的干预措施减少子宫内膜癌的种族差异.
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