青少年和年轻人的脑瘤成像:2021年世卫组织对基于分子的瘤类型的更新
Matthias W Wagner1, Pejman Jabehdar Maralani1, Julie Bennett1
1From the Division of Neuroradiology, Department of Diagnostic Imaging (M.W.W., S.L., B.B.E.W.), Division of Hematology/Oncology (J.B., L.N., U.T., V.R.), Department of Paediatric Laboratory Medicine, Division of Pathology (C.H.), Division of Neurosurgery (P.D.), and Division of Pediatric Neuroradiology (M.W.W.), The Hospital for Sick Children, 555 University Ave, Toronto, ON, Canada M5G 1X8; Neurosciences & Mental Health Research Program, SickKids Research Institute, Toronto, Canada (M.W.W., B.B.E.W.); Department of Medical Imaging, University of Toronto, Toronto, Canada (M.W.W., P.J.M., B.B.E.W.); Department of Diagnostic and Interventional Neuroradiology, University Hospital Augsburg, Augsburg, Germany (M.W.W.); Divisions of Neuroradiology (P.J.M.) and Neurooncology (M.J.L.F.), Sunnybrook Health Science Centre, Toronto, Canada; and Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Canada (J.B.).
2021年世卫组织中枢神经系统瘤分类影响青少年和年轻成年人 (AYA). 放射科医生需要在AYA中识别儿科和成人类型的大脑瘤,因为死亡率正在上升.
科学领域:
- 神经瘤学神经瘤学
- 分子诊断学 分子诊断学
- 放射学 放射学是指放射学
背景情况:
- 2021年世界卫生组织 (WHO) 中枢神经系统瘤分类纳入了新的分子标准.
- 青少年和年轻人 (AYA) 患有儿科类型和成人类型的中枢神经系统瘤.
- 中枢神经系统瘤死亡率在AYA中正在增加.
研究的目的:
- 审查与AYA相关的中枢神经系统瘤分类.
- 突出AYA中常见的儿科和成人类型脑瘤的成像特征.
- 讨论AYA质瘤分类的更新.
主要方法:
- 2021年世卫组织中枢神经系统瘤分类的审查 (第5版).
- 在AYA人群中普遍存在的中枢神经系统瘤类型的分析.
- 讨论分子子组和与年龄相关的瘤行为的差异.
主要成果:
- 质瘤是AYA中最常见的恶性中枢神经系统瘤 (约. 80%) 的情况.
- 扩散的天体细胞和神经神经瘤是常见的.
- 膜瘤和脑髓母细胞瘤不太常见,但在AYA中发生.
结论:
- 熟悉最新的世卫组织分类和成像对AYA至关重要.
- 了解特定年龄的瘤行为和分子子组是必要的.
- 本综述有助于放射科医生在AYA中诊断和管理中枢神经系统瘤.
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