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相关概念视频

Magnetic Resonance Imaging01:24

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
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高分辨率的前列腺扩散MRI使用形优化扩散编码和基于随机矩阵理论的无声化.

Zhaohuan Zhang1,2, Elif Aygun1,2, Shu-Fu Shih1,2

  • 1Department of Radiological Sciences, University of California Los Angeles, 300 UCLA Medical Plaza, Suite B119, Los Angeles, CA, 90095, USA.

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概括

这项研究引入了一种新的MRI技术,它结合了形优化扩散编码 (ENCODE) 与随机矩阵理论 (RMT) 的无声化. 改进的方法显著改善了前列腺扩散权重成像 (DWI) 的信号噪声比和准确性.

关键词:
拒绝这种行为,就是拒绝.扩散式核磁共振成像 (MRI)高分辨率扩散核磁共振成像前列腺 前列腺前列腺随机矩阵理论是随机矩阵理论.

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科学领域:

  • 磁共振成像是一种磁共振成像技术.
  • 生物医学工程 生物医学工程
  • 放射学 放射学是一门学科.

背景情况:

  • 前列腺扩散加权MRI (DWI) 对于癌症检测至关重要.
  • 提高高分辨率DWI需要增强的信号噪声比 (aSNR) 和准确的表面扩散系数 (ADC) 映射.
  • 加快获取时间对于临床可行性至关重要.

研究的目的:

  • 开发和评估一种技术,将形优化扩散编码 (ENCODE) 与基于随机矩阵理论 (RMT) 的无声化结合起来.
  • 在高分辨率前列腺DWI中加速和改进aSNR和ADC映射.
  • 评估ADC测量的精度和准确性.

主要方法:

  • 怀疑患有前列腺癌的11名受试者使用高分辨率 (HR) ENCODE和标准分辨率双极DWI序列进行了3TMRI.
  • HR-ENCODE数据被追溯分析,以减少重复以加速获取.
  • 基于随机矩阵理论 (RMT) 的无声化利用复杂的DWI信号和主要组件分析来消除噪音.

主要成果:

  • 与HR-ENCODE相比,基于RMT的HR-ENCODE与RMT无声化 (HR-ENCODE-RMT) 显示了与HR-ENCODE相比显著更高的中位数aSNR (62%在PZ,56%在TZ).
  • HR-ENCODE-RMT实现了较低的ADC变化系数 (CoV) (63%在PZ,70%在TZ),表明精度有所提高.
  • 从HR-ENCODE-RMT进行的ADC测量显示,与双极性ADC参考值相比,平均差异很小.

结论:

  • HR-ENCODE-RMT有效地缩短了高分辨率前列腺DWI的获取时间.
  • 该技术显著提高aSNR,并提供准确,精确的ADC测量.
  • 这种方法有望改善使用DWI的前列腺癌诊断.