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Updated: Jul 2, 2026

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一种替代方法,为实验性测试建立早期急性眼球毒素菌模型

Carlla Assis de Araujo-Silva1,2, Milena Ribeiro Peclat-Araujo1,2, Wanderley de Souza1,2

  • 1Laboratório de Ultraestrutura Celular Hertha Meyer, Centro de Pesquisa em Medicina de Precisão, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho, Cidade Universitária, Rio de Janeiro, RJ, 21941-904, Brazil.

International ophthalmology
|February 13, 2024
PubMed
概括

一种使用ME49-GFPtachyzoites的新小鼠模型有效地复制了急性眼球毒,使得可靠的视网膜病变研究和潜在的治疗方法.

关键词:
在体内测试试验 in vivo测试.小鼠急性毒素菌症眼部损伤监测 眼部损伤监测

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Toxoplasmosis01:28

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Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...