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Updated: Jul 3, 2025

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使用控制词汇的自动应用标准化提取的数据

Caroline Foster1, Jessica Wignall1, Samuel Kovach1

  • 1ICF, Durham, North Carolina, USA.

Environmental health perspectives
|February 13, 2024
PubMed
概括

自动化工具标准化了毒理学数据,提高了人类健康风险评估的效率. 这种方法提高了监管指南研究的数据可访问性和可重复使用性.

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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