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Updated: Jul 3, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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基因酶对CXCR3下游的偏向信号进行差异调节,这取决于它们的亚细胞局部

Julia Gardner1, Dylan Scott Eiger2, Chloe Hicks1

  • 1Trinity College, Duke University, Durham, NC 27710, USA.

Science signaling
|February 13, 2024
PubMed
概括

GPCR激酶 (GRKs) 通过将G蛋白合受体 (GPCRs) 引导到不同的细胞位置,从而导致偏差信号传递. 这种位置偏差影响下游的信号通路,揭示了复杂的配体-受体-GRK相互作用.

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