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Updated: Jul 3, 2025

Author Spotlight: Modeling Brain Tumors In Vivo Using Electroporation-Based Delivery of Plasmid DNA Representing Patient Mutation Signatures
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使用基因组编辑技术在小鼠中生成质母细胞瘤多样体模型的更有效的方法

Naoki Ohtsu1, Shota Katayama2

  • 1Division of Stem Cell Biology, Institute for Genetic Medicine, Hokkaido University, Japan; Celaid Therapeutics Co., LTD, Japan.

Biochemical and biophysical research communications
|February 13, 2024
PubMed
概括

研究人员开发了一种更有效的CRISPR/Cas9方法,以创建多形质母细胞瘤的小鼠模型. 这种新技术从野生类型的神经干细胞中诱导质瘤发起细胞 (GIC),为癌症研究提供了一个有前途的框架.

关键词:
基因组编辑 基因组编辑质瘤发起细胞的细胞.鼠标模型模型

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