利科哈尔科恩A诱导线粒体依赖的亡,并在急性髓性白血病中与venetoclax相互作用

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Updated: Jul 3, 2025

Detection of Mitochondria Membrane Potential to Study CLIC4 Knockdown-induced HN4 Cell Apoptosis In Vitro
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Detection of Mitochondria Membrane Potential to Study CLIC4 Knockdown-induced HN4 Cell Apoptosis In Vitro

Published on: July 17, 2018

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Youhong Li1, Mengting Zhao2, Ye Lin2

  • 1Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, China; Department of Pathology and Pathogenic Biology, and Zhejiang Key Laboratory of Pathophysiology, School of Basic Medical Sciences, Health Science Center, Ningbo University, Ningbo, China; Institute of Hematology, Ningbo University, Ningbo, China.

European journal of pharmacology
|February 13, 2024
PubMed
概括

一种天然化合物Licochalcone A (LCA) 有效地降低了急性髓性白血病 (AML) 细胞活力,并诱导了细胞亡. 作为一种治疗剂,LCA显示出前景,提高了venetoclax在AML治疗中的疗效.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.细胞灭亡 (apoptosis) 是一种死亡的过程.利科哈尔科尼 A 型威尼托克拉克斯 (Venetoclax) 是一个属于威尼托克拉克斯的地区.c-Myccc 的意思是我的

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