食品生物活性:功能超越苦味
Silvia Tagliamonte1, Veronica Oliviero1, Paola Vitaglione1
1Department of Agricultural Sciences, University of Naples Federico II, Portici, Italy.
Nutrition reviews
|February 13, 2024
概括
在食物中发现的苦类与全身的苦味受体 (TAS2Rs) 相互作用. 研究表明,这些可以提供超越味道的健康益处,为功能性食品铺平道路.
科学领域:
- 食品科学 食品科学 食品科学
- 药理学 药理学是指药理学的学科.
- 营养 营养 营养 营养 营养
背景情况:
- 由于苦味受体 (TAS2Rs) 的多态性,苦味的感知是基因变化的.
- TAS2Rs不仅存在于口腔,还存在于胃肠道,影响各种生理过程.
- 来自食物蛋白质的苦可以被TAS2Rs识别,并可以引起生物反应.
研究的目的:
- 审查有关苦的证据,包括它们的食物来源,形成和生物活动.
- 探索苦味生物活性的潜力,作为个性化营养的功能成分.
- 确定研究缺口和未来利用苦的方向.
主要方法:
- 关于苦的研究的文献综述.
- 对酸的分析,在食物和消化过程中的形成,以及生物活动.
- 检查苦的当前和潜在应用.
主要成果:
- 酸中的苦味与C端的疏水性氨基酸有关.
- 虽然研究往往侧重于减少苦味,但苦味具有生物活性,如抗高血压,抗糖尿病,抗氧化和增强免疫力的作用.
- 目前正在探索封装技术,以从苦中开发补充剂.
结论:
- 苦生物活性代表了个性化营养和精密医学中功能性食品开发的有希望的途径.
- 用苦来向胃肠道中的TAS2Rs,可以调节食欲,运动力和不适.
- 需要进一步的研究来优化技术策略,增强稳定性,并通过体内研究验证疗效.
相关概念视频
The Physiology of Taste
3.9K
The perception of a salty flavor is facilitated by sodium ions within the oral salivary fluid. Upon consumption of a salty substance, salt crystals disassemble, leading to the liberation of its constituents—Na+ and Cl- ions. These ions subsequently dissolve into the salivary fluid present in the oral cavity. The external environment of the gustatory cells experiences an elevation in Na+ concentration, thereby establishing a potent concentration gradient. This gradient propels the...
3.9K
Protein Digestion
103.6K
Protein digestion begins in the stomach, where the highly acidic environment can easily disrupt protein structure by exposing the peptide bonds of polypeptide chains. After polypeptide chains are broken into individual amino acids by a series of digestive enzymes, the amino acids are transported to the liver via the bloodstream to produce energy.
103.6K
Gustation
47.9K
Gustation is a chemical sense that, along with olfaction (smell), contributes to our perception of taste. It starts with the activation of receptors by chemical compounds (tastants) dissolved in the saliva. The saliva and filiform papillae on the tongue distribute the tastants and increase their exposure to the taste receptors.
47.9K
Taste Buds and Receptors
2.0K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
2.0K
Antimicrobial Proteins
992
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
992
Tagging and Fusion Proteins
6.6K
Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...
6.6K


