相关实验视频
Updated: Jul 3, 2025
04:27
Intratracheal Instillation of Stem Cells in Term Neonatal Rats
Published on: May 4, 2020
5.7K
产后类固醇用于第四期护理NICU中的支气管肺形
Uthayakumaran Kanagaraj1, Jason Tan1, Amuchou Soraisham2
1Department of Pediatrics, Neonatal Division, University of British Columbia, Vancouver, British Columbia, Canada.
American journal of perinatology
|February 13, 2024
概括
产后类固醇 (PNS) 给了8%的早产婴儿,使用稳定但增加剂量用于支气管肺功能障碍症 (BPD). 这项研究强调了PNS管理的变化,并建议采取干预措施,以优化对早产婴儿的护理.
科学领域:
- 新生儿科学 新生儿科学
- 儿科肺病学 儿科肺病学
- 临床药理学 临床药理学
背景情况:
- 产后类固醇 (PNS) 在早产婴儿中用于支气管肺功能障碍 (BPD) 的使用显示了中心间变异.
- 了解PNS管理的中心内模式对于开发有针对性的干预措施以改善结果至关重要.
- 本研究的重点是分析PNS在单个四级新生儿重症监护室 (NICU) 的使用情况.
研究的目的:
- 量化PNS在早产婴儿中的使用比例和描述PNS使用模式.
- 分析PNS方案中的时间,类型,趋势和偏差.
- 描述接受PNS的婴儿的临床特征和结果.
主要方法:
- 在四级NICU中进行了一项队列研究.
- 包括在2011年至2021年期间为BPD接受PNS的妊娠33周前出生的婴儿.
- 收集的数据包括PNS比例,类型,开始年龄,持续时间,趋势,治疗方案偏差和临床结果.
主要成果:
- 8%的婴儿 (<33周) 接受了PNS,总体使用稳定,但BPD累计中位数剂量增加了56%.
- 德克萨米他是最常见的初始PNS (85%),其中39%接受多个疗程.
- 近三分之一的PNS剂量用于非BPD适应症,46%的婴儿偏离了已公布的治疗方案.
结论:
- 增加PNS使用的变化,治疗方案的偏差和非BPD适用症需要有针对性的干预措施.
- 这些发现为优化NICU内的PNS管理流程提供了洞察力.
- 特定中心的干预措施可以帮助最大限度地减少临床实践的差异,并改善早产儿的护理.
相关概念视频
01:26COPD: Management Using Bronchodilators and Corticosteroids
206
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
206
01:25Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids
247
Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
247
01:17Drugs Used in Lower Respiratory Disorders: Overview
442
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
442
01:30Asthma-IV: Nursing Management
3.1K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
First, in...
3.1K
01:23Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
285
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
285
01:28Pneumonia IV: Management
327
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
327