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Updated: Jul 3, 2025

Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure
08:25

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用毒动力学-毒动力学模型预测金属混合物毒性,考虑时间依赖的不良结果路径

Lanpeng Yang1,2, Jing Zeng3, Ning Gao1

  • 1Key Laboratory of Pollution Process and Environmental Criteria of Ministry of Education, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin 300071, P. R. China.

Environmental science & technology
|February 13, 2024
PubMed
概括

这项研究将不良结果途径 (AOP) 与毒动力学-毒动力学 (TK-TD) 模型相结合,以预测金属混合物的毒性. 这种新的方法准确地预测了化学混合物随时间的推移而产生的影响,从而提高了生态毒理风险评估.

关键词:
负面结果的途径.遗传反应 遗传反应这是一种金属混合物.混合物的毒性 混合物的毒性毒性催化毒性动力学模型斑马鱼是一种斑马鱼.

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