在急性中耳炎中,细菌病原体和抗菌素耐药性
Amaia Sánchez Arlegui1, Jorge Del Arco Rodríguez1, Xabier De Velasco Vázquez1
1Servicio de Urgencias de Pediatría, Hospital Universitario Cruces, Instituto de Investigación Sanitaria Biocruces Bizkaia, Universidad del País Vasco, UPV/EHU, Barakaldo, País Vasco, Spain.
血型流感是儿童中耳炎 (AOM) 的主要原因. 这一发现表明,目前用于AOM的高剂量阿莫西西林治疗可能需要重新评估,因为病原体患病率发生变化.
科学领域:
- 儿童传染病 儿童传染病
- 微生物学 微生物学
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 急性中耳炎 (AOM) 是一种常见的儿童感染.
- 最近的趋势表明Haemophilus influenzae的增加和Streptococcus pneumoniae作为AOM的致病原体的下降.
研究的目的:
- 分析导致AOM的细菌病原体在14岁以下儿童中的分布.
- 为了研究这些病原体的抗微生物耐药性模式.
主要方法:
- 儿科AOM病例的回顾性,单中心研究.
- 从2013-2021年对耳道排水培养样本的分析.
- 包括被诊断患有AOM的14岁以下患者.
主要成果:
- 最常见的病原体是Hemophilus influenzae (24.5%),其中15.5%的病原体对安培素有耐药性.
- 肺炎链球菌的发病率较少 (6.9%),而青素耐药性中等 (9.4%).
- 在34.9%的病例中没有分离出任何病原体.
结论:
- 海莫菲勒斯流感是儿童AOM的主要原因.
- 肺炎链球菌 (Streptococcus pneumoniae) 患病率下降和对青素耐药性挑战了对高剂量阿莫西西林用于AOM的标准实证使用.
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