胆道血管和 retrobulbar 眼球血流变化与甲状腺相关的眼科医疗活动之间的相关性:一个横截面研究
Xinghong Sun1, Mengru Su1, Xiaowen Zhang2
1Department of Ophthalmology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, No.321, Zhongshan Road, Gulou District, Nanjing, 210000, China.
BMC ophthalmology
|February 13, 2024
概括
活跃的甲状腺相关轨道病 (TAO) 显示 retrobulbar 血流量增加和胆道血管化. 这些变化与临床活性和严重程度相关,为TAO进展提供了洞察力.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 医疗成像医学成像
背景情况:
- 甲状腺相关轨道病 (TAO) 是一种影响眼的自身免疫性疾病.
- 了解TAO中的血管变化对于评估疾病活动和严重程度至关重要.
- 彩色多普勒成像 (CDI) 和光学连贯断层扫描 (OCTA) 是评估眼血管系统的关键成像方法.
研究的目的:
- 为了评估TAO患者的逆膜CDI和胆道/视网膜OCTA参数.
- 确定这些成像参数与TAO的临床活性和严重性的关联.
主要方法:
- 使用CDI测量PCA,CRA和OA的逆气泡流量参数 (RI,PI,PSV,EDV).
- 视网膜和胸腔血管 (SVD,DVD,CHT,TCA,LA,SA,CVI) 使用OCTA进行了评估.
- 根据临床活动得分 (CAS) 将患者分为活跃和不活跃的TAO.
主要成果:
- 在活跃和不活跃的TAO组之间观察到CAS,proptosis,ChT,LA和CVI的显著差异.
- 与不活跃的患者相比,活跃的TAO患者表现出较高的PSV和后动脉EDV (PCA).
- 临床活动评分 (CAS) 与PCA的PSV有很强的相关性,而proptosis与ChT,LA,SA和CVI有关.
结论:
- 在活性TAO中,冠状管血管化和逆泡血流都会升高.
- 特定的冠状动脉循环变量与TAO的临床表现密切相关.
- CDI和OCTA参数为TAO的病理生理学和临床状态提供了宝贵的见解.
相关概念视频
Open Angle Glaucoma: Treatment
449
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
449
Glaucoma: Overview
571
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
571


