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Updated: Jul 3, 2025

Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells
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从大鼠多能干细胞诱导原始生殖细胞样细胞

Mami Oikawa1,2, Masumi Hirabayashi3,4, Toshihiro Kobayashi5,6

  • 1Division of Mammalian Embryology, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

Methods in molecular biology (Clifton, N.J.)
|February 14, 2024
PubMed
概括

研究人员开发了一种老鼠模型,用于在实验室中从多能干细胞 (PSC) 诱导原始生殖细胞样细胞 (PGCLC). 这一突破有助于了解细胞命运,动物育种和生殖医学.

关键词:
细胞聚合 细胞聚合 细胞聚合类似于表皮质细胞的细胞阴道体细胞是阴道体细胞.原始的生殖细胞类细胞.鼠的多能干细胞是什么

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Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
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