在一个健康的视角中,聚乙烯离子体电阻
Rikki Franklin Frederiksen1, Jannice Schau Slettemeås1, Silje Granstad1
1Department of Animal Health, Welfare and Food Safety, Norwegian Veterinary Institute, Ås, Norway.
Frontiers in microbiology
|February 14, 2024
概括
在动物料中使用的聚乙烯离子体 (PI) 可能会增加抗菌素耐药性. 本综述从"一个健康"的角度研究PI耐药性及其对人类健康的潜在风险.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 抗菌素耐药性 (AMR) 构成了全球健康的重大威胁.
- 在畜牧业中使用抗微生物药物有助于抵抗性病原体的传播.
- 聚乙烯离子体 (PI) 是畜牧业中广泛使用的抗微生物料添加剂.
研究的目的:
- 审查关于聚乙烯离子体 (PI) 电阻的当前知识.
- 讨论与PI在动物料中的使用相关的潜在人类健康风险.
- 在One Health框架内分析PI耐药性.
主要方法:
- 关于PI耐药性的科学出版物的文献综述.
- 对基因编码的PI耐药机制的分析.
- 研究阻力基因的等离子体介导的同局部化.
主要成果:
- 已经确定了PI耐药性的遗传编码机制.
- 对PI和医学上重要的抗微生物药物的耐药性基因在可转移等离子体上一起发现.
- 这种共同局部化引发了人们对交叉抵抗和抵抗的传播的担忧.
结论:
- 使用PI作为料添加剂可能有助于传播抗菌素耐药性.
- 对人类健康的潜在风险需要一个健康的方法来管理PI使用.
- 需要进一步的研究,以充分理解和减轻PI耐药性的One Health影响.
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