电场对动力皮层刺激能力的微小影响,其次是阳极tDCS
Ilkka Laakso1, Keisuke Tani2, Jose Gomez-Tames3
1Department of Electrical Engineering and Automation, Aalto University, 02150 Espoo, Finland.
iScience
|February 14, 2024
概括
阳道横直流刺激 (tDCS) 有效地增加了运动唤起潜力 (MEP). 然而,个体大脑电场变化并不能显著解释tDCS响应的差异.
科学领域:
- 神经科学是一个神经科学.
- 神经调节是一种神经调节.
- 发动机控制器的控制器
背景情况:
- 超直流刺激 (tDCS) 是一种神经调节技术,其剂量反应特征不确定.
- tDCS效应的变化可能源于影响大脑电场的个体解剖差异.
研究的目的:
- 为了研究电场在运动皮层对无极tDCS的反应的影响.
- 为了确定个性化电场建模是否可以解释响应变化.
主要方法:
- 随机交叉设计与21名参与者.
- 在0.5,1.0,1.5或2.0mA的10分钟阳极tDCS,或假设条件.
- 测量发动机唤起潜力 (MEP) 和计算单个运动皮层电场.
主要成果:
- 与假装相比,所有活跃的tDCS条件都显著增加了正常化的MEP大小.
- 运动皮层中计算的电场对正常化的MEP大小产生了非线性但很小的影响.
- 除了电场强度之外,参与者特定的因素对MEP响应变异性产生了更大的影响.
结论:
- 阳道tDCS有效地提高了运动皮层刺激能力,这是增加MEP大小所表明的.
- 在这项研究中,个性化电场建模在解释个人tDCS响应变异性方面没有提供显著的好处.
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