两个副甲状腺癌病例与多个棕色瘤相关
Akihiro Sakai1, Toshihide Inagi1, Hiroaki Iijima1
1Department of Otolaryngology, Head and Neck Surgery, Tokai University, School of Medicine, Isehara, Kanagawa 259-1193, Japan.
BJR case reports
|February 14, 2024
概括
罕见的甲状腺癌病例呈现出棕色瘤,模仿骨转移. 像99mTc-MIBI或18F-FDG PET/CT这样的成像很难区分. 副甲状腺切除术证实了诊断,改善了骨损伤.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 甲状腺癌是一种罕见的内分泌恶性瘤.
- 棕色瘤是与甲状腺功能障碍症相关的良性骨病变.
- 在甲状腺癌中区分棕色瘤与骨转移是临床上具有挑战性的.
研究的目的:
- 报告两例罕见的副甲状腺癌与多个棕色瘤的病例.
- 为了突出使用成像技术区分棕色瘤与骨转移的诊断困难.
- 强调在偏甲状腺癌骨病变的差异诊断中考虑棕色瘤的重要性.
主要方法:
- 两名患有甲状腺癌和棕色瘤的患者的病例介绍.
- 使用普通放射,计算机断层扫描和部超声波进行初步评估.
- 采用99mTc-methoxy isobutyl isonitrile (99mTc-MIBI) 和18F-fluorodeoxyglucose-positron发射断层扫描 (18F-FDG PET) /CT进行进一步的成像.
- 经过偏甲状腺切除术后的组织病理学检查确认了诊断.
主要成果:
- 这两种病例都呈现出骨损伤和副甲状腺瘤.
- 图像 (99mTc-MIBI,18F-FDG PET/CT) 显示,难以区分骨转移与棕色瘤.
- 副甲状腺切除术导致瘤的组织病理学确认,随后骨损伤的自发改善.
结论:
- 棕色瘤可以模仿甲状腺癌中的骨转移.
- 准确的诊断需要考虑棕色瘤的潜力,尤其是成像发现.
- 副甲状腺切除术可以用于诊断和治疗,从而导致骨损伤的解决和避免不必要的手术.
相关概念视频
00:59The Parathyroid Glands
2.1K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
2.1K
02:07Tumor Progression
6.3K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.3K
01:30Skin Cancer
4.1K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.1K