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Updated: Jul 3, 2025

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可视化疾病相关突变对G蛋白核酸相互作用的影响

Kara Anazia1, Lucien Koenekoop2, Guillaume Ferré1,3

  • 1Department of Chemistry; University of Florida; Gainesville, FL, 32611; USA.

bioRxiv : the preprint server for biology
|February 14, 2024
PubMed
概括

刺激性G蛋白α子单元 (GαS) 的突变通过改变G蛋白的功能引起疾病. 这项研究揭示了特定的GαS突变如何破坏核酸结合和蛋白质相互作用,影响细胞信号传递.

关键词:
这是一种G蛋白质蛋白质,G蛋白质蛋白质.G蛋白结合受体 (GPCR) 是一种这是一个GTPase.癌症 癌症 癌症 癌症 癌症分子动力学 (MD) 是指分子动力学.核磁共振 (NMR) 是一种核磁共振技术.

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