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Updated: Jul 3, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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利用AlphaFold揭示hERG频道的结构性国家机密

Khoa Ngo1,2, Pei-Chi Yang1,2, Vladimir Yarov-Yarovoy1,2,3

  • 1Center for Precision Medicine and Data Science, University of California, Davis, California.

bioRxiv : the preprint server for biology
|February 14, 2024
PubMed
概括

AlphaFold2准确地预测了心脏离子通道形状,揭示了特定状态的药物相互作用和捕获机制. 这有助于更好地理解药物安全性和离子通道功能.

关键词:
阿尔法折叠是什么意思阿尔法折叠生物化学和化学生物学结构生物学和分子生物物理学电压调节通道的电压调节通道希尔格 (HERG) 是一个分子对接的分子对接.分子动力学模拟模拟

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