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Updated: Jul 3, 2025

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
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Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization

Published on: July 27, 2021

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使用替代控制定义来增加GWAS的统计能力

Sarah E Benstock, Katherine Weaver, John Hettema

    Research square
    |February 14, 2024
    PubMed
    概括

    本研究引入了全基因组关联研究 (GWAS) 的顺序模型,通过重新定义病例控制结果来增强统计能力. 这种方法增加了对遗传发现的力量,相当于样本大小增加了10%,用于遗传发现.

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