Sumac对成人心脏代谢参数的影响:随机对照试验的系统审查和元分析
Amirhosein Jafarpour1, Saeedeh Jalali1, Masoumeh Akhlaghi1
1Department of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Frontiers in nutrition
|February 14, 2024
概括
苏马克的消费显著改善了关键的心脏代谢标记,包括胆固醇,血糖和胰岛素抵抗. 这一元分析表明其作为改善心血管健康的饮食干预的潜力.
科学领域:
- 心血管健康与营养科学 心血管健康与营养科学
- 代谢综合征研究 代谢综合征研究
背景情况:
- 心血管参数关于Sumac消费的证据仍然存在争议.
- 之前的研究已经产生了相矛盾的结果,关于Sumac对心脏健康的影响.
研究的目的:
- 系统地评估Sumac消费对各种心血管和代谢参数的影响.
- 综合现有随机对照试验 (RCT) 的研究结果.
主要方法:
- 在PubMed-Medline,SCOPUS和ISI Web of Science的系统文献搜索,直到2023年1月.
- 使用加权平均差异 (WMD) 和95%置信区间 (CI) 的16个RCT (1,225名参与者) 的元分析.
- 进行了子组和元回归分析.
主要成果:
- 苏玛克显著降低低密度脂蛋白 (LDL),甘油三,禁食血糖,胰岛素和HOMA-IR.
- 在高密度脂蛋白 (HDL) 和人类指数中观察到显著改善.
- 总胆固醇的降低在12周或更长时间的干预期间是显著的.
结论:
- 苏玛克显示出作为改善心脏代谢参数的有效补充干预的潜力.
- 将Sumac纳入饮食可能会提高整体心脏代谢状态.
- 进一步的研究可以探索最佳剂量和长期影响.
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