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Updated: Jul 3, 2025

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尼古丁胺胺酸基转移酶 阳性 体调节剂 减弱神经元氧化应激

Jesse Gordon-Blake1, Kiira Ratia1,1, Victoria Weidig1

  • 1Department of Pharmaceutical Sciences, Research Resources Center, Department of Chemistry, and Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois 60612, United States.

ACS medicinal chemistry letters
|February 14, 2024
PubMed
概括

通过使用新型NAMPT阳性全调节剂 (N-PAMs) 提高尼古丁胺氨酸二核酸 (NAD+) 水平,可以抵消氧化应激. 这些N-PAMs在神经退行性疾病模型中减轻反应性氧物种 (ROS) 的承诺.

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