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在人类肝脏显微体中对CYP2C9,2D6和3A4的物理抑制

Lu Liu1, Sen Sun2, Xiaohua Li1

  • 1Department of Endocrine, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, PR China.

Pharmaceutical biology
|February 14, 2024
PubMed
概括

作为中国传统医学的成分,Physcion抑制了关键的P450酶 (CYP450s),如CYP2C9,CYP2D6和CYP3A4. 这种相互作用依赖于度,影响其临床用途.

关键词:
其他CYP450异型.拉巴巴是一种拉巴巴竞争性抑制是一种竞争性抑制.非竞争性抑制是一种非竞争性抑制.时间依赖的时间依赖.

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