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Updated: Aug 7, 2026

Transfection of Mouse Retinal Ganglion Cells by in vivo Electroporation
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一个灵活的电极阵列用于通过电穿孔通过视网膜的不同层的遗传传染

Yu Zhang1, Tao Peng1, Yu Ge2

  • 1Department of Biomedical Engineering, School of Medical Technology, Beijing Institute of Technology, Beijing 100081, China. weizewen@bit.edu.cn.

Lab on a chip
|February 14, 2024
PubMed
概括

一种用于视网膜电穿孔 (FERE) 的新型灵活微电极阵列显著降低了电压,并提高了基因传递的手术精度. 这项技术克服了以前的局限性,为视网膜基因疗法的临床应用铺平了道路.

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相关概念视频

G-Protein Gated Ion Channels01:21

G-Protein Gated Ion Channels

GPCRs are primarily responsible for our sense of smell, taste, and vision.  The binding of a sensory stimulus activates GPCR to stimulate effector proteins, many of which are ion channels in the sensory organs. GPCRs modulate the opening and closing of the target ion channels either directly by binding them, or by releasing second messengers that activate these channels. As ions move across the membrane, the membrane potential is altered, which induces an appropriate response.
Sensory organs,...